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Lithium diisopropylamide (LDA) is a well-known sterically hindered strong base, which is used for the formation of carbanions. Lithium diisopropylamide is widely applied as a metallating basic reagent and also serves as a sterically hindered non-nucleophilic strong base reagent, among other uses. 2.0 M solution in tetrahydrofuran/n-heptane/ethylbenzene (22%/35%/14%)